Animal models to achieve an HIV cure

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Animal Models for HIV Cure Research

The HIV-1/AIDS pandemic continues to spread unabated worldwide, and no vaccine exists within our grasp. Effective antiretroviral therapy (ART) has been developed, but ART cannot clear the virus from the infected patient. A cure for HIV-1 is badly needed to stop both the spread of the virus in human populations and disease progression in infected individuals. A safe and effective cure strategy f...

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Animal models in HIV cure research

Current HIV antiretroviral therapy (ART) successfully inhibits viral replication in the majority of HIV-infected individuals. However, ART is not curative and lifelong adherence is required. Despite the undisputed benefit of ART, long-lived latently infected cells that carry HIV-integrated DNA remain. Hence, upon ART interruption, HIV-infected subjects experience viral rebound. Interestingly, s...

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Preeclampsia: animal models for a human cure.

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ژورنال

عنوان ژورنال: Current Opinion in HIV and AIDS

سال: 2016

ISSN: 1746-630X

DOI: 10.1097/coh.0000000000000290